ENBREL* should be reconstituted aseptically with 1 mL of the supplied Sterile Bacteriostatic Water for Injection, USP (0.9% benzyl alcohol) giving a solution of 1.0 mL containing 25 mg of ENBREL*
A vial adapter is supplied for use when reconstituting the lyophilized powder
However, the vial adapter should not be used if multiple doses are going to be withdrawn from the vial
If the vial will be used for multiple doses, a 25-gauge needle should be used for reconstituting and withdrawing ENBREL*
Reconstitution with the supplied BWFI, using a 25-gauge needle, yields a preserved, multiple-use solution that must be used within 14 days
ENBREL* multiple-use vial is supplied in a carton containing four dose trays
Each dose tray contains one 25 mg vial of etanercept, one diluent syringe (1 mL Sterile Bacteriostatic Water for Injection, USP, containing 0.9% benzyl alcohol), one 27-gauge ˝-inch needle, one vial adapter, one plunger, and two alcohol swabs
Each carton contains four "Mixing Date" stickers
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